Attachment and Biobehavioral Catch-up (ABC) is an evidence-based home-visiting parenting program that partners with parents to support young children exposed to early adversity. A professor and researcher at the University of Delaware, Dr. Mary Dozier, developed ABC over 25 years ago and has rigorously tested the program through multiple randomized trials. For this research, there has been continued partnership between Dr. Dozier’s lab and communities deeply affected by historical racism and poverty. Remarkable results were found with children’s attachment, biological regulation, impulse control, language, brain development, and even DNA methylation that persist at least into adolescence. ABC is currently endorsed by the MIECHV-Home Visiting Coalition, The California Evidence-Based Clearing House for Child Welfare, and SAMHSA’s National Registry of Evidence-based Programs and Practices. We are also a collaborating member of the National Alliance of Home Visiting Models.